Thrombosis and Translational Platelet Function Research (AG Sibbing)

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The working group focuses on translational research on thrombosis and platelet function and on clinical trials in the field of antiplatelet treatment for patients undergoing PCI. Our aim is to develop innovative and safer antithrombotic treatment regimens for patients with acute coronary syndromes and for patients undergoing coronary stenting. Studying cardiogenic shock patients in this regard is also in the focus of our research.

In 2013, our group initiated the TROPICAL-ACS (TESTING RESPONSIVENESS TO PLATELET INHIBITION ON CHRONIC ANTIPLATELET TREATMENT FOR ACUTE CORONARY SYNDROMES) Trial (Clinicaltrials.gov identifier NCT01959451). This study is an investigator-initiated, prospective, randomized, parallel-group, open-label, multicenter trial designed to evaluate the benefits of personalized antiplatelet therapy in patients with acute coronary syndromes treated with percutaneous coronary intervention. The study will enroll 2600 patients from > 30 investigational centers across Europe.